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| Registros recuperados : 34 | |
| 1. |  | STAFUZZA, N. B.; CAETANO, A. R.; AMARAL, M. E. J. Mapeamento RH dos genes APOM, BDA20 e CRABP2 no genoma bovino. In: CONGRESSO BRASILEIRO DE GENÉTICA, 51., 2005, Águas de Lindóia, SP. A era da genômica: da bioestatística à bioinformática: anais. Ribeirão Preto, SP: Sociedade Brasileira de Genética, 2005. p. 194.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 4. | | VENTURINI, G. C.; STAFUZZA, N. B.; CARDOSO, D. F.; BALDI, F.; LEDUR, M. C.; DANTAS, J. de O.; EL FARO, L.; MUNARI, D. P. Association between ACTA1 candidate gene and performance, organs and carcass traits in broilers. Poultry Science, 16 out. 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 5. | | GRUPIONI, N. V.; STAFUZZA, N. B.; CARVAJAL, A. B.; IBELLI, A. M. G.; PEIXOTO, J. de O.; LEDUR, M. C.; MUNARI, D. P. Association of RUNX2 and TNFSF11 genes with production traits in a paternal broiler line. Genetics and Molecular Research, v. 16, n.1, 2017.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 6. | | PERIPOLLI, E.; STAFUZZA, N. B.; MACHADO, M. A.; PANETTO, J. C. do C.; EGITO, A. A. do; BALDI, F.; SILVA, M. V. G. B. Assessment of copy number variants in three Brazilian locally adapted cattle breeds using whole-genome re-sequencing data. Animal Genetics, v. 54, n. 3, p. 254-270, 2023.| Biblioteca(s): Embrapa Gado de Leite. |
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| 7. | | RODRIGUES FILHO, E. A.; STAFUZZA, N. B.; CAETANO, A. R.; GILL, C. A.; RIGGS, P. K.; WOMACK, J. E.; AMARAL, M. E. J. Mapping MHC genes in River Buffalo. In: PINARD, M. H.; GAY, C.; PASTORET, P. P.; DODET, B. (Ed.). Animal genomics for animal health. Basel: Karger, 2008. p. 343-346. (Developments in biologicals, v. 132)| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 8. | | FREITAS, L. A. de; GRUPIONI, N. V.; SAVEGNAGO, R. P.; STAFUZZA, N. B.; FIGUEIREDO, E. A. P. de; SCHMIDT, G. S.; LEDUR, M. C.; MUNARI, D. P. Non-hierarchical cluster analysis for body weight, age at first egg, egg production and egg weight in a laying hen strain. In: INTERNATIONAL MEETING OF ADVANCES IN ANIMAL SCIENCE, 2016, Jaboticabal. Posters presentations... Jabotical: PPGZ Unesp, 2016.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 9. | | BRUNES, L. C.; BALDI, F.; LOPES, F. B.; LOBO, R. B.; ESPIGOLAN, R.; COSTA, M. F. O. e; STAFUZZA, N. B.; MAGNABOSCO, C. de U. Weighted single-step genome-wide association study and pathway analyses for feed efficiency traits in Nellore cattle. Journal of Animal Breeding and Genetics, v. 138, n. 1, p. 23-44, Jan. 2021.| Biblioteca(s): Embrapa Arroz e Feijão; Embrapa Cerrados. |
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| 10. | | PERIPOLLI, E.; CHIAIA, H. L. J.; BERTON, M. P.; KLUSKA, S.; STAFUZZA, N. B.; MUNARI, D. P.; PANETTO, J. C. do C.; MACHADO, M. A.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B. Ilhas de homozigose para identificação de genes relacionados com características de importância econômica na pecuária leiteira em bovinos da raça Gir (Bos primigenius indicus) In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 12., 2017, Ribeirão Preto. Anais... Ribeirão Preto: SBMA, 2017. 3 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 11. | | CRUZ, V. A. R. da; SCHENKEL, F. S.; SAVEGNAGO, R. P.; GRUPIONI, N. V.; STAFUZZA, N. B.; SARGOZAEL, M.; IBELLI, A. M. G.; PEIXOTO, J. de O.; LEDUR, M. C.; MUNARI, D. P. Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line. Plos One, v. 10, n.8, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 12. | | SBARDELLA, A. P; FONSECA, I.; WELLER, M. A. DEL C. A.; STAFUZZA, N. B.; OLIVEIRA, J. R.; WATANABE, R. N.; COSTA, R, M. da; CARVAJAL, A. B.; SILVA, M. V. G. B.; MARTINS, M. F.; MUNARI, D. P. Avaliação de abordagens estatísticas para análise da expressão gênica diferencial em dados reais de RNA-seq In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 12., 2017, Ribeirão Preto. Anais... Ribeirão Preto: SBMA, 2017. 3 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 13. | | SBARDELLA, A. P.; FONSECA, I.; WELLER, M. M. D. C. A.; STAFUZZA, N. B.; OLIVEIRA, J. R.; WATANABE, R. N.; COSTA, R. M. da; CARVAJAL, A. B.; SILVA, M. V. G. B.; MARTINS, M. F.; MUNARI, D. P. Avaliação de abordagens estatísticas para análise da expressão gênica diferencial em dados reais de RNA-Seq. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 12., 2017, Ribeirão Preto. Anais... Ribeirão Preto: SBMA, 2017.| Biblioteca(s): Embrapa Gado de Leite. |
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| 14. | | PERIPOLLI, E.; STAFUZZA, N. B.; MUNARI, D. P.; LIMA, A. L. F.; IRGANG, R.; MACHADO, M. A.; PANETTO, J. C. do C.; VENTURA, R. V.; BALDI, F.; SILVA, M. V. G. B. Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle. BMC Genomics, v. 19, n. 34, 2018. 13 p.| Biblioteca(s): Embrapa Gado de Leite. |
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| 15. | | VERARDO, L. L.; STAFUZZA, N. B.; MUNARI, D. P.; ZERLOTINI NETO, A.; CHUD, T. C. S.; GARRICK, D. J.; COLE, J. B.; PANETTO, J. C. do C.; MACHADO, M. A.; MARTINS, M. F.; SILVA, M. V. G. B. A gene-transcription factor network associated with residual feed intake based on SNVs/InDels identified in Gir, Girolando and Holstein cattle breeds. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland. Proceedings... [S.l.: s.n.], 2018.| Biblioteca(s): Embrapa Gado de Leite. |
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| 16. | | VERARDO, L. L.; STAFUZZA, N. B.; MUNARI, D. P.; ZERLOTINI NETO, A.; CHUD, T. C. S.; GARRICK, D. J.; COLE, J. B.; PANETTO, J. C. do C.; MACHADO, M. A.; MARTINS, M. F.; SILVA, M. V. G. B. A gene-transcription factor network associated with residual feed intake based on SNVs/InDels identified in Gir, Girolando and Holstein cattle breeds. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland. Proceedings... [S.l.: s.n.], 2018. 6 p. Na publicação: A. Zerlotini, J. C. C. Panetto. WCGALP 2018.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 17. | | STAFUZZA, N. B.; SILVA, R. M. de O.; PERIPOLLI, E.; BEZERRA, L. A. F.; LOBO, R. B.; MAGNABOSCO, C. de U.; DI CROCE, F.; OSTERSTOCK, J.; MUNARI, D. P.; LOURENCO, D. A. L.; BALDI, F. Genome-wide association study provides insights into genes related with horn development in Nelore beef cattle. PLoS ONE, v. 13, n. 8, e0202978, August 30, 2018.| Biblioteca(s): Embrapa Cerrados. |
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| 18. | | RAGOGNETTI, B. do N. N; STAFUZZA, N. B.; SILVA, T. B. R. da; CHUD, T. C. S.; GRUPIONI, V. A. R.; CRUZ, V. A. R.; DANTAS, J. de O.; NONES, K.; LEDUR, M. C.; MUNARI, D. P. Genetic parameters and mapping quantitative trait loci associated with tibia traits in broilers. Genetics and Molecular Research, v. 14, n. 4, p. 17544-17554, 2015.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 19. | | ZERLOTINI NETO, A.; STAFUZZA, N. B.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; SILVA, M. V. G. B. Detection of potential genetic variants affecting gene function in Guzerat cattle. In: INTERNATIONAL CONFERENCE OF THE AB3C, 12., 2016, Belo Horizonte. Proceedings... [S.l.]: AB3C, 2016. p. 47. X-meeting 2016.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 20. | | ZERLOTINI NETO, A.; STAFUZZA, N. B.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; SILVA, M. V. G. B. Detection of potential genetic variants affecting gene function in Guzerat cattle. In: INTERNATIONAL CONFERENCE OF THE AB3C, 12., 2016, Belo Horizonte. Proceedings... [S.l.]: AB3C, 2016. p. 47. X-meeting 2016.| Biblioteca(s): Embrapa Agricultura Digital. |
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| Registros recuperados : 34 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Cerrados. |
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Data corrente: |
12/12/2018 |
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Data da última atualização: |
12/12/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
STAFUZZA, N. B.; SILVA, R. M. de O.; PERIPOLLI, E.; BEZERRA, L. A. F.; LOBO, R. B.; MAGNABOSCO, C. de U.; DI CROCE, F.; OSTERSTOCK, J.; MUNARI, D. P.; LOURENCO, D. A. L.; BALDI, F. |
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Afiliação: |
Nedenia Bonvino Stafuzza, UNESP; Rafael Medeiros de Oliveira Silva, University of Georgia; ELISA PERIPOLLI, UNESP; Luiz Antônio Framartino Bezerra, USP; Raysildo Barbosa Lôbo, Associaçao Nacional dos Criadores e Pesquisadores; CLAUDIO DE ULHOA MAGNABOSCO, CPAC; Fernando Di Croce, Zoetis; Jason Osterstock, Zoetis; Danísio Prado Munari, UNESP; Daniela A. Lino Lourenco, University of Georgia; Fernando Baldi, UNESP. |
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Título: |
Genome-wide association study provides insights into genes related with horn development in Nelore beef cattle. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
PLoS ONE, v. 13, n. 8, e0202978, August 30, 2018. |
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DOI: |
https://doi.org/10.1371/journal.pone.0202978 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract The causal mutation for polledness in Nelore (Bos taurus indicus) breed seems to have appeared first in Brazil in 1957. The expression of the polled trait is known to be ruled by a few groups of alleles in taurine breeds; however, the genetic basis of this trait in indicine cattle is still unclear. The aim of this study was to identify genomic regions associated with the hornless trait in a commercial Nelore population. A total of 107,294 animals had phenotypes recorded and 2,238 were genotyped/imputed for 777k SNP. The weighted single-step approach for genome-wide association study (WssGWAS) was used to estimate the SNP effects and variances accounted for by 1 Mb sliding SNP windows. A centromeric region of chromosome 1 with 3.11 Mb size (BTA1: 878,631?3,987,104 bp) was found to be associated with hornless in the studied population. A total of 28 protein-coding genes are mapped in this region, including the taurine Polled locus and the IFNAR1, IFNAR2, IFNGR2, KRTAP11-1, MIS18A, OLIG1, OLIG2, and SOD1 genes, which expression can be related to the horn formation as described in literature. The functional enrichment analysis by DAVID tool revealed cytokine-cytokine receptor interaction, JAK-STAT signaling, natural killer cell mediated cytotoxicity, and osteoclast differentiation pathways as significant (P < 0.05). In addition, a runs of homozygosity (ROH) analysis identified a ROH island in polled animals with 2.47 Mb inside the region identified by WssGWAS. Polledness in Nelore cattle is associated with one region in the genome with 3.1 Mb size in chromosome 1. Several genes are harbored in this region, and they may act together in the determination of the polled/horned phenotype. Fine mapping the locus responsible for polled trait in Nelore breed and the identification of the molecular mechanisms regulating the horn growth deserve further investigation. MenosAbstract The causal mutation for polledness in Nelore (Bos taurus indicus) breed seems to have appeared first in Brazil in 1957. The expression of the polled trait is known to be ruled by a few groups of alleles in taurine breeds; however, the genetic basis of this trait in indicine cattle is still unclear. The aim of this study was to identify genomic regions associated with the hornless trait in a commercial Nelore population. A total of 107,294 animals had phenotypes recorded and 2,238 were genotyped/imputed for 777k SNP. The weighted single-step approach for genome-wide association study (WssGWAS) was used to estimate the SNP effects and variances accounted for by 1 Mb sliding SNP windows. A centromeric region of chromosome 1 with 3.11 Mb size (BTA1: 878,631?3,987,104 bp) was found to be associated with hornless in the studied population. A total of 28 protein-coding genes are mapped in this region, including the taurine Polled locus and the IFNAR1, IFNAR2, IFNGR2, KRTAP11-1, MIS18A, OLIG1, OLIG2, and SOD1 genes, which expression can be related to the horn formation as described in literature. The functional enrichment analysis by DAVID tool revealed cytokine-cytokine receptor interaction, JAK-STAT signaling, natural killer cell mediated cytotoxicity, and osteoclast differentiation pathways as significant (P < 0.05). In addition, a runs of homozygosity (ROH) analysis identified a ROH island in polled animals with 2.47 Mb inside the region identified by WssGWAS. Pollednes... Mostrar Tudo |
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Thesagro: |
Bos Indicus; Gado Nelore; Mutação. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/188280/1/Genome-wide-association-study-provides-apagar.pdf
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Marc: |
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008 2018 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1371/journal.pone.0202978$2DOI
100 1 $aSTAFUZZA, N. B.
245 $aGenome-wide association study provides insights into genes related with horn development in Nelore beef cattle.$h[electronic resource]
260 $c2018
520 $aAbstract The causal mutation for polledness in Nelore (Bos taurus indicus) breed seems to have appeared first in Brazil in 1957. The expression of the polled trait is known to be ruled by a few groups of alleles in taurine breeds; however, the genetic basis of this trait in indicine cattle is still unclear. The aim of this study was to identify genomic regions associated with the hornless trait in a commercial Nelore population. A total of 107,294 animals had phenotypes recorded and 2,238 were genotyped/imputed for 777k SNP. The weighted single-step approach for genome-wide association study (WssGWAS) was used to estimate the SNP effects and variances accounted for by 1 Mb sliding SNP windows. A centromeric region of chromosome 1 with 3.11 Mb size (BTA1: 878,631?3,987,104 bp) was found to be associated with hornless in the studied population. A total of 28 protein-coding genes are mapped in this region, including the taurine Polled locus and the IFNAR1, IFNAR2, IFNGR2, KRTAP11-1, MIS18A, OLIG1, OLIG2, and SOD1 genes, which expression can be related to the horn formation as described in literature. The functional enrichment analysis by DAVID tool revealed cytokine-cytokine receptor interaction, JAK-STAT signaling, natural killer cell mediated cytotoxicity, and osteoclast differentiation pathways as significant (P < 0.05). In addition, a runs of homozygosity (ROH) analysis identified a ROH island in polled animals with 2.47 Mb inside the region identified by WssGWAS. Polledness in Nelore cattle is associated with one region in the genome with 3.1 Mb size in chromosome 1. Several genes are harbored in this region, and they may act together in the determination of the polled/horned phenotype. Fine mapping the locus responsible for polled trait in Nelore breed and the identification of the molecular mechanisms regulating the horn growth deserve further investigation.
650 $aBos Indicus
650 $aGado Nelore
650 $aMutação
700 1 $aSILVA, R. M. de O.
700 1 $aPERIPOLLI, E.
700 1 $aBEZERRA, L. A. F.
700 1 $aLOBO, R. B.
700 1 $aMAGNABOSCO, C. de U.
700 1 $aDI CROCE, F.
700 1 $aOSTERSTOCK, J.
700 1 $aMUNARI, D. P.
700 1 $aLOURENCO, D. A. L.
700 1 $aBALDI, F.
773 $tPLoS ONE$gv. 13, n. 8, e0202978, August 30, 2018.
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Embrapa Cerrados (CPAC) |
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